Heparinase 1 selectivity for the 3,6-di-O-sulfo-2-deoxy-2- sulfamido-α-D-glucopyranose (1,4) 2-O-sulfo-α-L- idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages
نویسندگان
چکیده
Zhongping Xiao2,3, Wenjing Zhao4, Bo Yang3, Zhenqing Zhang3, Huashi Guan1,2, and Robert J Linhardt1,3,4,5 Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drug and Food, Ocean University of China, Qingdao 266003, China; Department of Chemistry and Chemical Biology, Department of Biology, and Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
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High cell density cultivation of recombinant Escherichia coli strains expressing 2-O-sulfotransferase and C5-epimerase for the production of bioengineered heparin.
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تاریخ انتشار 2010